Article
Molecular characterization of the p(un) allele of the mouse pink-eyed dilution locus.
Pigment cell research - 1 Nov 1992
Brilliant M H, Gondo Y
Abstract excerpt
The mouse pink-eyed dilution locus, p, located on chromosome 7, mediates coat and eye color. The human correlate of this gene may underlie some forms of tyrosinase-positive oculocutaneous albinism. Mutations at the p locus result in a reduction in pigmentation of the eyes and coat. Although most mutant p alleles (including all spontaneous mutations) affect only pigmentation, several mutant alleles (all radiation...
Topics
- Albinism, Oculocutaneous
- Alleles
- Animals
- Blotting, Southern
- Chromosome Mapping
- Chromosomes, Human, Pair 7
- DNA
- Eye Color
- Genes
- Homozygote
- Humans
- Mice