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Article

Comprehensive screening of the human KRAS2 gene for sequence variants.

Genes, chromosomes & cancer - 1 Feb 1993

Abrams E S, Murdaugh S E, Lerman L S

Abstract excerpt

To search for mutations in the human KRAS2 oncogene, we have analyzed polymerase chain reaction (PCR) fragments by denaturing gradient gel electrophoresis. We used six different PCR fragments to screen the five coding exons of this gene as well as the splice sites. GC clamps were added to each fragment by means of heteroduplex extension. We infer, from a theoretical analysis in which we employed the computer...

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Identifiers

PMID: 7680891
DOI: 10.1002/gcc.2870060203

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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