Rapid screening assay for KRAS mutations by the modified smart amplification process.

doi:10.2353/jmoldx.2008.080024

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Community

Back to search

Article

Rapid screening assay for KRAS mutations by the modified smart amplification process.

The Journal of molecular diagnostics : JMD - 1 Nov 2008

Tatsumi Kenji, Mitani Yasumasa, Watanabe Jun, Takakura Hideki, Hoshi Kanako, Kawai Yuki, Kikuchi Takeshi, Kogo Yasushi, Oguchi-Katayama Atsuko, Tomaru Yasuhiro, Kanamori Hajime, Baba Masaru, Ishidao Takefumi, Usui Kengo, Itoh Masayoshi, Cizdziel Paul E, Lezhava Alexander, Ueda Michio, Ichikawa Yasushi, Endo Itaru, Togo Shinji, Shimada Hiroshi, Hayashizaki Yoshihide

Abstract excerpt

Previously, the smart amplification process version 2 (SMAP-2) was developed to detect mutations from tissue and in crude cell lysates and has been used for rapid diagnosis of specific somatic mutations with single-nucleotide precision. The purpose of this study was to develop a rapid and practical method to detect cancer and metastasis in specimens using the SMAP-2 assay. We developed modified SMAP-2 assays that...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aged, 80 and over

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to DNA Mutational Analysis

Share to Nucleic Acid Amplification Techniques

Share to Point Mutation

Share to Proto-Oncogene Proteins

Share to Proto-Oncogene Proteins p21(ras)

Share to ras Proteins

Share to Sensitivity and Specificity

Source

Open in PubMed Open full text

Identifiers

PMID: 18832461
DOI: 10.2353/jmoldx.2008.080024
PMCID: PMC2570635

Genes

KRAS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Rapid screening assay for KRAS mutations by the modified smart amplification process.PMID 18832461Read ↗

Usefulness of peptide nucleic acid (PNA)-clamp smart amplification process version 2 (SmartAmp2) for clinical diagnosis of KRAS codon 12 mutations in lung adenocarcinoma: comparison of PNA-clamp SmartAmp2 and PCR-related methods.Semantic proximity Read ↗

Detection of SNP by the isothermal smart amplification method.Semantic proximity Read ↗

Clinical screening assay for EGFR exon 19 mutations using PNA-clamp smart amplification process version 2 in lung adenocarcinoma.Semantic proximity Read ↗

Rapid and cost-effective SNP detection method: application of SmartAmp2 to pharmacogenomics research.Semantic proximity Read ↗

A PNA-mediated clamping PCR for routine detection of KRAS mutations in colorectal carcinoma.Semantic proximity Read ↗

Modified PNA-PCR method: a convenient and accurate method to screen plasma KRAS mutations of cancer patients.Semantic proximity Read ↗

Mutation detection of epidermal growth factor receptor and KRAS genes using the smart amplification process version 2 from formalin-fixed, paraffin-embedded lung cancer tissue.Semantic proximity Read ↗

Hot-Spot-Specific Probe (HSSP) for Rapid and Accurate Detection of KRAS Mutations in Colorectal Cancer.Semantic proximity Read ↗

Sensitive and quantitative detection of KRAS2 gene mutations in pancreatic duct juice differentiates patients with pancreatic cancer from chronic pancreatitis, potential for early detection.Semantic proximity Read ↗

Performance evaluation of a CRISPR Cas9-based selective exponential amplification assay for the detection of KRAS mutations in plasma of patients with advanced pancreatic cancer.Semantic proximity Read ↗

SNaPshot and StripAssay as valuable alternatives to direct sequencing for KRAS mutation detection in colon cancer routine diagnostics.Semantic proximity Read ↗

Detection of KRAS codon 12 and 13 mutations by mutant-enriched PCR assay.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.