Article
Detecting changes in the relative expression of KRAS2 splice variants using polymerase colonies.
Biotechnology progress - 1 Jan 2000
Butz James A, Roberts Kim G, Edwards Jeremy S
Abstract excerpt
Because splice variants of a gene with multiple isoforms give rise to proteins with different functions, it seems plausible that changes in the expression levels of the splice variants could be a contributing factor to disease. In fact, recent examples in the literature clearly illustrate that altered expression levels of splice variants may play an important role in disease. Furthermore, these works demonstrate...
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