Article
Ultrasensitive detection of KRAS2 mutations in bile and serum from patients with biliary tract carcinoma using LigAmp technology.
The Journal of molecular diagnostics : JMD - 1 Nov 2009
Shi Chanjuan, Chandrasekaran Arjun, Thuluvath Paul J, Karikari Collins, Argani Pedram, Goggins Michael, Maitra Anirban, Eshleman James R
Abstract excerpt
Patients with biliary tract carcinoma have a poor prognosis. Early detection efforts are urgently needed to ameliorate the dismal prognosis for these patients. Mutations of the KRAS2 gene are one of the most common genetic aberrations in this cancer. In this study, we used LigAmp, an ultrasensiti...
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