Article
Characteristic patterns of HOX gene expression in different types of human leukemia.
International journal of cancer - 21 Jan 1993
Celetti A, Barba P, Cillo C, Rotoli B, Boncinelli E, Magli M C
Abstract excerpt
Homeobox-containing genes are a network of genes encoding DNA-binding proteins highly conserved throughout evolution. They are involved in the control of normal development as well as in the regulation of gene expression in adult differentiating systems, including hematopoiesis. Aberrant expression of homeobox-containing genes has recently been related to leukemic phenotype. Human homeobox-containing genes of the...
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