Article
Serotonergic 5-HT1A receptors regulate a cell contact-mediated interaction between natural killer cells and monocytes.
Scandinavian journal of immunology - 1 Jan 1993
Hellstrand K, Hermodsson S
Abstract excerpt
Autologous monocytes irreversibly suppressed functions of human natural killer (NK) cells including baseline and lymphokine-induced cytotoxicity, antibody-dependent cellular cytotoxicity (ADCC), and interleukin-2 (IL-2)-induced proliferation. The suppression of these NK-cell functions was cell co...
Topics
- Antibody-Dependent Cell Cytotoxicity
- Antigens, CD
- Antigens, Differentiation, T-Lymphocyte
- CD3 Complex
- CD56 Antigen
- Cell Communication
- Cells, Cultured
- Cytotoxicity, Immunologic
- Down-Regulation
- Humans
- Killer Cells, Natural
- Monocytes
- Phenotype
- Receptors, IgG
- Receptors, Serotonin
- Serotonin