Article
Production of anti-acetylcholine receptor-alpha antibody in vitro by peripheral blood lymphocytes of patients with myasthenia gravis: role of immunoregulatory T cells and monocytes.
The Journal of laboratory and clinical medicine - 1 Aug 1994
Ofosu-Appiah W, Mokhtarian F, Shirazian D, Grob D
Abstract excerpt
To study the role of T cells in T and B cell interaction resulting in production of antibody (Ab) to the alpha chain of acetylcholine receptor (anti-AChR-alpha Ab) in myasthenia gravis (MG), we cocultured peripheral blood-purified B and T cells of patients with MG and of control subjects with and...
Topics
- Adult
- Aged
- Aged, 80 and over
- Antibodies, Monoclonal
- Antibody Formation
- B-Lymphocytes
- CD4 Antigens
- CD8 Antigens
- Cell Communication
- Cells, Cultured
- Female
- Histocompatibility Antigens Class II
- Humans
- Indomethacin
- Male
- Middle Aged
- Monocytes
- Myasthenia Gravis