A cell-to-cell mediated interaction involving monocytes and non-T/CD16+ natural killer (NK) cells is required for histamine H2-receptor-mediated NK-cell activation.

doi:10.1111/j.1365-3083.1990.tb02814.x

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Article

A cell-to-cell mediated interaction involving monocytes and non-T/CD16+ natural killer (NK) cells is required for histamine H2-receptor-mediated NK-cell activation.

Scandinavian journal of immunology - 1 May 1990

Hellstrand K, Hermodsson S

Abstract excerpt

Histamine (10(-4) to 10(-7) M) augmented natural killer cell cytotoxicity (NKCC) of human CD16+, non-T lymphocytes in vitro against the NK-sensitive target cells K562 erythroleukaemic, Molt-4 lymphoma, Chang liver cells and against Epstein-Barr virus (EBV)-transformed, NK-insensitive Daudi B-lymphoblastoid target cells by a mechanism of action involving a prostaglandin- and interleukin 1 (IL-1)-independent...

Topics

Antigens, Differentiation
Cell Communication
Cell Line
Histamine
Humans
Interferons
Interleukin-1
Interleukin-2
Killer Cells, Natural
Kinetics
Lymphocyte Activation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Monocytes

Phenotype

Prostaglandin-Endoperoxide Synthases

Protein Biosynthesis

Receptors, Fc

Receptors, Histamine H2

Receptors, IgG

Source

Open in PubMed

Identifiers

PMID: 1693229
DOI: 10.1111/j.1365-3083.1990.tb02814.x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1693229-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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