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Article

Effects of parenteral recombinant human macrophage colony-stimulating factor on monocyte number, phenotype, and antitumor cytotoxicity in nonhuman primates.

Blood - 15 May 1990

Munn D H, Garnick M B, Cheung N K

Abstract excerpt

Recombinant human macrophage colony-stimulating factor (rhM-CSF) was given to cynomolgus monkeys by continuous intravenous infusion or subcutaneous injection, at a dose of 50 to 100 micrograms/kg/d in repetitive 14-day cycles. Starting within 24 to 48 hours of initiation of rhM-CSF, there was a p...

Topics

Animals
Antibody-Dependent Cell Cytotoxicity
Cell Count
Colony-Stimulating Factors
Leukocytes
Macaca fascicularis
Macrophage Colony-Stimulating Factor
Male
Monocytes
Phenotype
Recombinant Proteins

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PMID: 2186820

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-2186820-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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