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Article

Preservation of immune effector cell function following administration of a dose-intense 5-fluorouracil-chemotherapy regimen.

Cancer immunology, immunotherapy : CII - 1 Jan 1993

Weiner L M, Hudes G R, Kitson J, Walczak J, Watts P, Litwin S, O'Dwyer P J

Abstract excerpt

In a phase II clinical trial of 5-fluorouracil (5FU) plus N-(phosphonacetyl)-L-aspartate (PALA) therapy administration, a number of slowly developing clinical responses were observed. Because of this, a variety of immune parameters were sequentially studied in 21 patients on this trial. Of the 21 patients studied, 20 provided sufficient samples to compare baseline with subsequent values, 10 of the 20 patients...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 8439979
DOI: 10.1007/BF01741090
PMCID: PMC11038605

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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