Article
Normal distribution of apolipoprotein E alleles in progressive supranuclear palsy.
Neurology - 1 Apr 1996
Anouti A, Schmidt K, Lyons K E, Hubble J P, Schellenberg G, Golbe L I, Lang A E, Galvez-Jimenez N, Hershey L, Koller W C
Abstract excerpt
Apolipoprotein E (Apo E) genotype is a genetic risk factor influencing the development of Alzheimer's disease (AD). Progressive supranuclear palsy (PSP), like AD, is a dementing illness with neurofibrillary tangles. We determined the frequencies of Apo E alleles in 52 PSP patients and 52 age- and gender-matched controls. The distribution of Apo E allele frequencies and genotypes showed no difference between PSP...
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