Article
Abnormal Purkinje cell dendrites in lurcher chimeric mice result from a deafferentation-induced atrophy.
Journal of neurobiology - 1 Mar 1996
Soha J M, Herrup K
Abstract excerpt
Previous studies of Purkinje cell dendrites in lurcher<-->wild-type mouse chimeras (lurcher chimeras) have documented the surprising occurrence of unusual atrophic dendritic morphologies among the wild-type cells of the mosaic cerebella. We have hypothesized that these aberrant morphologies arise from a process of developmental deafferentation that is due to the unique loss of mutant Purkinje cells in these...
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