Article
Subcellular localisation of human wee1 kinase is regulated during the cell cycle
1 Jun 1995
Abstract excerpt
Wee1 kinase-dependent phosphorylation of cdc2 maintains the cdc2/cyclin B complex in an inert form until it is activated by the cdc25 tyrosine phosphatase at the end of G2. As described for cdc25, cell cycle-linked changes in the intracellular localisation of wee1 may constitute an important aspect of the temporal regulation of cdc2 activity. Here we report that the subcellular distribution of human wee1 changes...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
