Article
The complete 685-kilobase DNA sequence of the human beta T cell receptor locus.
Science (New York, N.Y.) - 21 Jun 1996
Rowen L, Koop B F, Hood L
Abstract excerpt
The human beta T cell receptor (TCR) locus, comprising a complex family of genes, has been sequenced. The locus contains two types of coding elements--TCR elements (65 variable gene segments and two clusters of diversity, joining, and constant segments) and eight trypsinogen genes --that constitu...
Topics
- Amino Acid Sequence
- Base Sequence
- Biological Evolution
- Chromosomes, Human, Pair 7
- Chromosomes, Human, Pair 9
- DNA, Complementary
- Exons
- Genetic Variation
- Humans
- Introns
- Molecular Sequence Data
- Multigene Family
- Polymorphism, Genetic
- Promoter Regions, Genetic
- Pseudogenes
- RNA Splicing
- Receptors, Antigen, T-Cell, alpha-beta
- Repetitive Sequences, Nucleic Acid