Modified multiple drug resistance phenotype of Chinese hamster ovary cells selected with X-rays and vincristine versus X-rays only.

doi:10.1038/bjc.1994.134

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Back to search

Article

Modified multiple drug resistance phenotype of Chinese hamster ovary cells selected with X-rays and vincristine versus X-rays only.

British journal of cancer - 1 Apr 1994

McClean S, Hill B T

Abstract excerpt

Exposure of Chinese hamster ovary (CHO) cells to fractionated X-irradiation [ten fractions of 9 Gray (Gy)] resulted in the expression of a multiple drug resistance phenotype which was distinct from that of drug-selected cells in two features: (i) resistance to vinca alkaloids and epipodophyllotox...

Topics

ATP Binding Cassette Transporter, Subfamily B, Member 1
Animals
CHO Cells
Carrier Proteins
Cell Line
Cricetinae
Doxorubicin
Drug Resistance
Gene Expression Regulation, Neoplastic
Membrane Glycoproteins
Phenotype
Protein Processing, Post-Translational
Rhodamines
Vincristine

Source

Open in PubMed Open full text

Identifiers

PMID: 7908216
DOI: 10.1038/bjc.1994.134
PMCID: PMC1968820

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-7908216-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics