Susceptibility to astrocytoma and meningioma: influence of allelism at glutathione S-transferase (GSTT1 and GSTM1) and cytochrome P-450 (CYP2D6) loci.

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Article

Susceptibility to astrocytoma and meningioma: influence of allelism at glutathione S-transferase (GSTT1 and GSTM1) and cytochrome P-450 (CYP2D6) loci.

Cancer research - 1 Oct 1995

Elexpuru-Camiruaga J, Buxton N, Kandula V, Dias P S, Campbell D, McIntosh J, Broome J, Jones P, Inskip A, Alldersea J

Abstract excerpt

We describe a case-control study to identify associations between polymorphism at the cytochrome P-450 (CYP2D6) and glutathione S-transferase (GSTT1 and GSTM1) loci and susceptibility to astrocytoma and meningioma. Accordingly, genotype frequencies in 112 astrocytoma and 50 meningioma patients we...

Topics

Adult
Aged
Alleles
Astrocytoma
Case-Control Studies
Cytochrome P-450 CYP2D6
Cytochrome P-450 Enzyme System
Female
Genotype
Glutathione Transferase
Humans
Isoenzymes

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Male

Meningeal Neoplasms

Meningioma

Middle Aged

Mixed Function Oxygenases

Regression Analysis

Source

Open in PubMed

Identifiers

PMID: 7671227

Genes

GSTM1
GSTT1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-7671227-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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