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Article

CYP2D6 genetic polymorphisms are associated with susceptibility to pituitary tumors.

Acta medica portuguesa - 1 Jan 2000

Gomes Leonor, Lemos Manuel C, Paiva Isabel, Ribeiro Cristina, Carvalheiro Manuela, Regateiro Fernando J

Abstract excerpt

Several polymorphisms of drug-metabolizing enzymes have been implicated in the susceptibility to tumor development. The role of the CYP2D6, GSTM1 and GSTT1 genes has been extensively studied, with alleles conferring different metabolic efficiencies and tumor risk. We studied the relationship between the main polymorphisms of these genes and the susceptibility to develop pituitary tumors, by performing a...

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Source

Identifiers

PMID: 16611538

Genes

GSTM1
GSTT1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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