Allelism at the glutathione S-transferase GSTM3 locus: interactions with GSTM1 and GSTT1 as risk factors for astrocytoma.

doi:10.1093/carcin/17.9.1919

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Article

Allelism at the glutathione S-transferase GSTM3 locus: interactions with GSTM1 and GSTT1 as risk factors for astrocytoma.

Carcinogenesis - 1 Sept 1996

Hand P A, Inskip A, Gilford J, Alldersea J, Elexpuru-Camiruaga J, Hayes J D, Jones P W, Strange R C, Fryer A A

Abstract excerpt

We describe studies to assess the influence of polymorphism in the human glutathione S-transferase GSTM3 gene on susceptibility to high grade astrocytoma. Immunohistochemical studies using a GSTM3-specific antiserum identified expression of the GSTM3 subunit in astrocytes. The relative levels of...

Topics

Alleles
Astrocytoma
Base Sequence
Brain
Brain Neoplasms
Cytosol
Gene Frequency
Genotype
Glutathione Transferase
Humans
Isoenzymes
Risk Factors

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