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Article

Identification of glutathione S-transferase (GST) polymorphisms in brain tumors and association with susceptibility to pediatric astrocytomas.

Journal of neuro-oncology - 1 Sept 2002

Ezer Rona, Alonso Michelle, Pereira Elaine, Kim Mimi, Allen Jeffrey C, Miller Douglas C, Newcomb Elizabeth W

Abstract excerpt

Polymorphisms in the glutathione S-transferase (GST) genes, a superfamily that plays a key role in carcinogen metabolism, have been associated with an increased susceptibility to several types of cancer. We wished to evaluate whether variant allelic forms of GST isoenzymes were associated with an increased susceptibility for brain tumors and age of tumor onset. Here, we examined 394 brain tumors (221 adult and...

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Source

Identifiers

PMID: 12241105
DOI: 10.1023/a:1019601305210

Genes

GSTP1
GSTM1
GSTT1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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