Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genetic polymorphism of CYP2D6, GSTM1 and NAT2 and susceptibility to haematological neoplasias.

Carcinogenesis - 1 Jul 1999

Lemos M C, Cabrita F J, Silva H A, Vivan M, Plácido F, Regateiro F J

Abstract excerpt

Xenobiotic-metabolizing enzymes constitute an important line of defence against a variety of carcinogens. Many are polymorphic, constituting the basis for the wide inter-individual variation in metabolic capacity and possibly a source of variation in the susceptibility to chemical-induced carcinogenesis. The aim of this study was to determine the existence of any association between the main genetic polymorphisms...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Arylamine N-Acetyltransferase
Share to Cytochrome P-450 CYP2D6

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Gene Frequency

Share to Genetic Linkage

Share to Glutathione Transferase

Share to Hematologic Neoplasms

Share to Homozygote

Share to Odds Ratio

Source

Identifiers

PMID: 10383893
DOI: 10.1093/carcin/20.7.1225

Genes

GSTM1
NAT2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genetic polymorphism of CYP2D6, GSTM1 and NAT2 and susceptibility to haematological neoplasias.PMID 10383893Read ↗

CYP2D6 genetic polymorphisms are associated with susceptibility to pituitary tumors.Semantic proximity Read ↗

Genetic polymorphism of N-acetyltransferase-2, glutathione S-transferase-M1, and cytochromes P450IIE1 and P450IID6 in the susceptibility to head and neck cancer.Semantic proximity Read ↗

Genetic polymorphism and cancer risk.Semantic proximity Read ↗

Genotype and allele frequencies of N-acetyltransferase 2 and glutathione S-transferase in the Iranian population.Semantic proximity Read ↗

[Genetic and phenotypic polymorphisms in carcinogen-metabolizing enzymes and cancer susceptibility].Semantic proximity Read ↗

CYP1A1 and CYP2D6 Polymorphisms and Susceptibility to Chronic Myelocytic Leukaemia.Semantic proximity Read ↗

[Genetic polymorphisms in xenobiotic metabolizing enzymes as a determinant of susceptibility to environmental mutagens and carcinogens in humans].Semantic proximity Read ↗

Association of CYP1A1 and CYP2D6 gene polymorphisms with head and neck cancer in Tunisian patients.Semantic proximity Read ↗

Genetic polymorphism of CYP1A1, CYP2D6, GSTM1 and GSTT1 and susceptibility to acute lymphoblastic leukaemia in Indian children.Semantic proximity Read ↗

Human drug-metabolizing enzyme polymorphisms: effects on risk of toxicity and cancer.Semantic proximity Read ↗

Polymorphisms in NAT2, CYP2D6, CYP2C19 and GSTP1 and their association with prostate cancer.Semantic proximity Read ↗

Genetic susceptibility to childhood acute lymphoblastic leukemia.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.