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Article

A tumour necrosis factor alpha polymorphism is not associated with rheumatoid arthritis.

Annals of the rheumatic diseases - 1 Jul 1995

Wilson A G, de Vries N, van de Putte L B, Duff G W

Abstract excerpt

OBJECTIVE: To determine whether a polymorphism within the tumour necrosis factor alpha (TNF alpha) gene is associated with susceptibility to, or severity of, rheumatoid arthritis (RA). METHODS: Consecutive patients with recent onset RA were enrolled in a prospective trial. DNA was collected, disease activity was measured at presentation, and radiographic progression at three years was assessed. Typing of TNF...

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Identifiers

PMID: 7668906
DOI: 10.1136/ard.54.7.601
PMCID: PMC1009943

Genes

TNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Research trail→

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A tumour necrosis factor alpha polymorphism is not associated with rheumatoid arthritis.PMID 7668906Read ↗

TNF-alpha -308 promoter polymorphism in patients with rheumatoid arthritis.Semantic proximity Read ↗

TNF +489 polymorphism does not contribute to susceptibility to rheumatoid arthritis.Semantic proximity Read ↗

TNF-alpha gene polymorphism does not affect the clinical and radiological outcome of rheumatoid arthritis.Semantic proximity Read ↗

Meta-analysis identified the TNFA -308G > A promoter polymorphism as a risk factor for disease severity in patients with rheumatoid arthritis.Semantic proximity Read ↗

No association of polymorphisms in the tumor necrosis factor receptor I and receptor II genes with disease severity in rheumatoid arthritis.Semantic proximity Read ↗

Lack of tumor necrosis factor alpha gene polymorphism -857c/t (rs1799724) association in Pakistani rheumatoid arthritis patients.Semantic proximity Read ↗

Genetic variants in toll-like receptors are not associated with rheumatoid arthritis susceptibility or anti-tumour necrosis factor treatment outcome.Semantic proximity Read ↗

Polymorphisms in the tumour necrosis factor gene are not associated with severity of inflammatory polyarthritis.Semantic proximity Read ↗

TNF Nco-I RFLP is not an independent risk factor in rheumatoid arthritis.Semantic proximity Read ↗

Tumour necrosis factor alpha gene polymorphisms in rheumatoid arthritis: association with susceptibility to, or severity of, disease?Semantic proximity Read ↗

Tumor necrosis factor (TNF) and TNFR1 polymorphisms are not risk factors for rheumatoid arthritis in a Mexican population.Semantic proximity Read ↗

Association between rheumatoid arthritis and polymorphism of tumor necrosis factor receptor II, but not tumor necrosis factor receptor I, in CaucasiansSemantic proximity Read ↗

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