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Article

Polymorphisms in the tumour necrosis factor gene are not associated with severity of inflammatory polyarthritis.

Annals of the rheumatic diseases - 1 Mar 2004

Barton A, Platt H, Salway F, Symmons D, Barrett E, Bukhari M, Lunt M, Zeggini E, Eyre S, Hinks A, Tellam D, Brintnell B, Ollier W, Worthington J, Silman A

Abstract excerpt

BACKGROUND: Tumour necrosis factor alpha (TNFalpha) is a powerful inflammatory mediator in rheumatoid and other types of inflammatory arthritis. Polymorphisms within the TNFalpha gene have previously been investigated to determine their role in the aetiopathogenesis of rheumatoid arthritis (RA), but it is unclear whether reported associations are with susceptibility to, or severity of, disease. OBJECTIVE: To...

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Identifiers

PMID: 14962963
DOI: 10.1136/ard.2003.008680
PMCID: PMC1754913

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ACR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Polymorphisms in the tumour necrosis factor gene are not associated with severity of inflammatory polyarthritis.PMID 14962963Read ↗

A tumour necrosis factor alpha polymorphism is not associated with rheumatoid arthritis.Semantic proximity Read ↗

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Investigation of polymorphisms in the PADI4 gene in determining severity of inflammatory polyarthritis.Semantic proximity Read ↗

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The influence of HLA-DRB1 alleles and rheumatoid factor on disease outcome in an inception cohort of patients with early inflammatory arthritis.Semantic proximity Read ↗

Tumour necrosis factor gene polymorphisms as severity markers in rheumatoid arthritisSemantic proximity Read ↗

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