Article
No association of polymorphisms in the tumor necrosis factor receptor I and receptor II genes with disease severity in rheumatoid arthritis.
The Journal of rheumatology - 1 Jul 2003
Glossop John R, Nixon Nicola B, Dawes Peter T, Hassell Andrew B, Mattey Derek L
Abstract excerpt
OBJECTIVE: A recent Italian study found that homozygosity for the G allele of the +196 single nucleotide polymorphism (SNP) of the tumor necrosis factor receptor II (TNFRSF1B) gene was more prevalent in patients with severe rheumatoid arthritis (RA). We investigated whether this particular SNP, and also one at position +36 in exon 1 of the TNF receptor I (TNFRSF1A) gene, are associated with disease severity....
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.