Association of arylamine N-acetyltransferases NAT1 and NAT2 genotypes to laryngeal cancer risk.

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Article

Association of arylamine N-acetyltransferases NAT1 and NAT2 genotypes to laryngeal cancer risk.

Pharmacogenetics - 1 Feb 1999

Henning S, Cascorbi I, Münchow B, Jahnke V, Roots I

Abstract excerpt

Genetically polymorphic xenobiotic metabolizing enzymes are supposed to be host factors for an individual's cancer susceptibility. A total of 255 laryngeal cancer patients was genotyped for NAT1 and NAT2 and compared with 510 reference individuals, matched by age and gender. NAT1 genotypes (NAT1*3, *4, *10, and *11 ) were found equally distributed between cases and control individuals. However, there was a...

Topics

Adult
Aged
Aged, 80 and over
Alcohol Drinking
Arylamine N-Acetyltransferase
Base Sequence
DNA Primers
Female
Genetic Predisposition to Disease
Genotype
Humans
Isoenzymes
Laryngeal Neoplasms
Male
Middle Aged
Risk Factors
Smoking

Source

Open in PubMed

Identifiers

PMID: 10208649

Genes

NAT2
NAT1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

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