Evidence for two unlinked loci regulating total serum IgE levels.

Article

Evidence for two unlinked loci regulating total serum IgE levels.

American journal of human genetics - 1 Aug 1995

Xu J, Levitt R C, Panhuysen C I, Postma D S, Taylor E W, Amelung P J, Holroyd K J, Bleecker E R, Meyers D A

Abstract excerpt

Studies investigating the genetic control of total serum IgE levels are of major importance in understanding basic pathophysiologic mechanisms in atopy and asthma, since IgE levels predict onset and correlate with the clinical expression of these disorders. Previous analysis of data from 92 famil...

Topics

Asthma
Chromosomes, Human, Pair 5
Genetic Linkage
Genotype
Humans
Immunoglobulin E
Lod Score
Models, Genetic

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