Article
Genome-wide association studies on IgE regulation: are genetics of IgE also genetics of atopic disease?
Current opinion in allergy and clinical immunology - 1 Oct 2010
Weidinger Stephan, Baurecht Hansjörg, Naumann Aline, Novak Natalija
Abstract excerpt
PURPOSE OF REVIEW: Total IgE levels are considered a useful endophenotype for studying the genetics of atopic diseases. However, the role and significance of genetic factors influencing IgE regulation for atopic diseases as endpoints is unclear. RECENT FINDINGS: Recently, genome-wide association studies (GWASs) have been applied to atopic traits with considerable success. A total of seven published GWASs on...
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