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Article

Segregation analysis of IgE levels in 335 French families (EGEA) using different strategies to correct for the ascertainment through a correlated trait (asthma).

Genetic epidemiology - 1 Feb 2000

Sampogna F, Demenais F, Hochez J, Oryszczyn M P, Maccario J, Kauffmann F, Feingold J, Dizier M H

Abstract excerpt

The main objective of this study was to search for a major gene controlling total serum immunoglobulin E (IgE) levels, an intermediate phenotype for asthma and allergy. We studied 335 French nuclear families of the EGEA study (Epidemiological study of the Genetics and Environment of Asthma), ascertained through asthmatic probands (123 are parents in the family, 212 children). Segregation analyses were performed...

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Identifiers

PMID: 10642426
DOI: 10.1002/(SICI)1098-2272(200002)18:2<128::AID-GEPI3>3.0.CO;2-9

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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