Article
Tissue factor promotes melanoma metastasis by a pathway independent of blood coagulation.
Proceedings of the National Academy of Sciences of the United States of America - 29 Aug 1995
Bromberg M E, Konigsberg W H, Madison J F, Pawashe A, Garen A
Abstract excerpt
Several studies have established a link between blood coagulation and cancer, and more specifically between tissue factor (TF), a transmembrane protein involved in initiating blood coagulation, and tumor metastasis. In the study reported here, a murine model of human melanoma metastasis was used for two experiments. (i) The first experiment was designed to test the effect of varying the level of TF expression in...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
