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Article

Increased metastatic potential of tumor cells in von Willebrand factor-deficient mice.

Journal of thrombosis and haemostasis : JTH - 1 Mar 2006

Terraube V, Pendu R, Baruch D, Gebbink M F B G, Meyer D, Lenting P J, Denis C V

Abstract excerpt

BACKGROUND: The key role played by von Willebrand factor (VWF) in platelet adhesion suggests a potential implication in various pathologies, where this process is involved. In cancer metastasis development, tumor cells interact with platelets and the vessel wall to extravasate from the circulation. As a potential mediator of platelet-tumor cell interactions, VWF could influence this early step of tumor spread and...

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Source

Identifiers

PMID: 16405520
DOI: 10.1111/j.1538-7836.2005.01770.x

Genes

VWF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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