Molecular mapping of SSRs for Pgm1 and C8b in the vicinity of the rat fatty locus.

doi:10.1006/geno.1995.1017

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Article

Molecular mapping of SSRs for Pgm1 and C8b in the vicinity of the rat fatty locus.

Genomics - 1 May 1995

Kershaw E E, Chua S C, Williams J A, Murphy E M, Leibel R L

Abstract excerpt

Recessive mutations at the rat fatty locus (fa, facp), which produce obesity, insulin resistance, and diabetes, provide useful experimental models for similar phenotypes in humans. The molecular pathogenesis of the metabolic phenotype in animals segregating for fa is unknown and difficult to study once the confounding metabolic effects of obesity are present. Although various experimental methods distinguish...

Topics

Alleles
Animals
Base Sequence
Complement C8
Crosses, Genetic
Diabetes Mellitus, Type 2
Disease Models, Animal
Female
Genes, Recessive
Genetic Linkage
Genetic Markers
Genetic Predisposition to Disease

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Insulin Resistance

Male

Molecular Sequence Data

Obesity

Phenotype

Phosphoglucomutase

Source

Open in PubMed

Identifiers

PMID: 7665162
DOI: 10.1006/geno.1995.1017

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-7665162-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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Molecular mapping of SSRs for Pgm1 and C8b in the vicinity of the rat fatty locus.PMID 7665162Read ↗

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