Article
Molecular mapping of SSRs for Pgm1 and C8b in the vicinity of the rat fatty locus.
Genomics - 1 May 1995
Kershaw E E, Chua S C, Williams J A, Murphy E M, Leibel R L
Abstract excerpt
Recessive mutations at the rat fatty locus (fa, facp), which produce obesity, insulin resistance, and diabetes, provide useful experimental models for similar phenotypes in humans. The molecular pathogenesis of the metabolic phenotype in animals segregating for fa is unknown and difficult to study once the confounding metabolic effects of obesity are present. Although various experimental methods distinguish...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
