Article
Utility of a C-jun microsatellite marker in determining gene dosage for fatty (fa).
Obesity research - 1 Nov 1993
Chua S C, Hansen M H, Truett G E, Leibel R L
Abstract excerpt
The Zucker fatty (fa) mutation provides a genetic model for obesity and non-insulin dependent diabetes mellitus. The molecular pathogenesis of the metabolic phenotype of these animals is not known. Detailed molecular maps of the region surrounding the fa locus on rat chromosome 5 can be used for positional cloning experiments as well as to permit genotyping of animals from appropriate crosses before the...
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