Article
Alcohol Dehydrogenase-1B (rs1229984) and Aldehyde Dehydrogenase-2 (rs671) Genotypes and Alcoholic Ketosis Are Associated with the Serum Uric Acid Level in Japanese Alcoholic Men.
Alcohol and alcoholism (Oxford, Oxfordshire) - 1 May 2016
Yokoyama Akira, Yokoyama Tetsuji, Mizukami Takeshi, Matsui Toshifumi, Kimura Mitsuru, Matsushita Sachio, Higuchi Susumu, Maruyama Katsuya
Abstract excerpt
AIMS: To identify determinants of hyperuricemia in alcoholics. METHODS: The serum uric acid (UA) levels of 1759 Japanese alcoholic men (≥40 years) were measured on their first visit or within 3 days after admission; ADH1B and ALDH2 genotyping on blood DNA samples were performed. Dipstick urinalyses for ketonuria and serum UA measurements were simultaneously performed for 621 men on their first visit. RESULTS:...
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