Article
A mutation in glyceraldehyde 3-phosphate dehydrogenase alters endocytosis in CHO cells.
The Journal of cell biology - 1 Sept 1995
Robbins A R, Ward R D, Oliver C
Abstract excerpt
The CHO cell mutant FD 1.3.25 exhibits both increased accumulation and altered distribution of endocytosed fluid phase tracers. Neither the rate of tracer internalization nor the kinetics of recycling from early endosomes was affected, but exocytosis from late endocytic compartments appeared to be decreased in the mutant. Endocytosed tracer moved more rapidly to the cell poles in FD1.3.25 than in wild type cells....
Topics
- Animals
- Base Sequence
- CHO Cells
- Cell Compartmentation
- Cloning, Molecular
- Cricetinae
- DNA, Complementary
- Endocytosis
- Fluorescent Dyes
- Gene Expression
- Glyceraldehyde-3-Phosphate Dehydrogenases