Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Mutational analysis of the putative effector domain of the GTP-binding Ypt1 protein in yeast suggests specific regulation by a novel GAP activity.

The EMBO journal - 1 Apr 1991

Becker J, Tan T J, Trepte H H, Gallwitz D

Abstract excerpt

Ypt1p of Saccharomyces cerevisiae is a ras-related GTP-binding protein that fulfils an essential function in intracellular protein transport between the endoplasmic reticulum (ER) and the Golgi complex. Ypt proteins from yeasts and mammals that share an identical sequence in the region analogous to the ras effector domain are functionally interchangeable. We analyzed the function of the putative effector domain...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Amino Acid Sequence
Share to Base Sequence
Share to Cloning, Molecular

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Escherichia coli

Share to Kinetics

Share to Molecular Sequence Data

Share to Phenotype

Share to Saccharomyces cerevisiae

Source

Open in PubMed Open full text

Identifiers

PMID: 2009858
DOI: 10.1002/j.1460-2075.1991.tb08010.x
PMCID: PMC452717

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Mutational analysis of the putative effector domain of the GTP-binding Ypt1 protein in yeast suggests specific regulation by a novel GAP activity.PMID 2009858Read ↗

The yeast SLY gene products, suppressors of defects in the essential GTP-binding Ypt1 protein, may act in endoplasmic reticulum-to-Golgi transport.Semantic proximity Read ↗

Identification and structure of four yeast genes (SLY) that are able to suppress the functional loss of YPT1, a member of the RAS superfamily.Semantic proximity Read ↗

Identification of regulators for Ypt1 GTPase nucleotide cycling.Semantic proximity Read ↗

Molecular cloning of YPT1/SEC4-related cDNAs from an epithelial cell line.Semantic proximity Read ↗

Functional implications of genetic interactions between genes encoding small GTPases involved in vesicular transport in yeast.Semantic proximity Read ↗

An essential role for a phospholipid transfer protein in yeast Golgi function.Semantic proximity Read ↗

Mutation of the Rab6 homologue of Saccharomyces cerevisiae, YPT6, inhibits both early Golgi function and ribosome biosynthesis.Semantic proximity Read ↗

Establishing a role for the GTPase Ypt1p at the late Golgi.Semantic proximity Read ↗

The Ypt1 GTPase is essential for the first two steps of the yeast secretory pathway.Semantic proximity Read ↗

A novel phospholipid-binding protein from the yeast Saccharomyces cerevisiae with dual binding specificities for the transport GTPase Ypt7p and the Sec1-related Vps33p.Semantic proximity Read ↗

Biochemical and genetic evidence for the involvement of yeast Ypt6-GTPase in protein retrieval to different Golgi compartments.Semantic proximity Read ↗

A Ypt32p Exchange Factor Is a Putative Effector of Ypt1pSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.