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Article

TRAPPII regulates exocytic Golgi exit by mediating nucleotide exchange on the Ypt31 ortholog RabERAB11.

Proceedings of the National Academy of Sciences of the United States of America - 7 Apr 2015

Pinar Mario, Arst Herbert N, Pantazopoulou Areti, Tagua Víctor G, de los Ríos Vivian, Rodríguez-Salarichs Javier, Díaz J Fernando, Peñalva Miguel A

Abstract excerpt

The oligomeric complex transport protein particle I (TRAPPI) mediates nucleotide exchange on the RAB GTPase RAB1/Ypt1. TRAPPII is composed of TRAPPI plus three additional subunits, Trs120, Trs130, and Trs65. Unclear is whether TRAPPII mediates nucleotide exchange on RAB1/Ypt1, RAB11/Ypt31, or both. In Aspergillus nidulans, RabO(RAB1) resides in the Golgi, RabE(RAB11) localizes to exocytic post-Golgi carriers...

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Identifiers

PMID: 25831508
DOI: 10.1073/pnas.1419168112
PMCID: PMC4394270

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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