Article
Use1p is a yeast SNARE protein required for retrograde traffic to the ER.
The EMBO journal - 15 Jul 2003
Dilcher Meik, Veith Beate, Chidambaram Subbulakshmi, Hartmann Enno, Schmitt Hans Dieter, Fischer von Mollard Gabriele
Abstract excerpt
SNAREs on transport vesicles and target membranes are required for vesicle targeting and fusion. Here we describe a novel yeast protein with a typical SNARE motif but with low overall amino acid homologies to other SNAREs. The protein localized to the endoplasmic reticulum (ER) and was therefore named Use1p (unconventional SNARE in the ER). A temperature-sensitive use1 mutant was generated. use1 mutant cells...
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