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Article

Temporally distinct patterns of p53-dependent and p53-independent apoptosis during mouse lens development.

Genes & development - 1 Sept 1995

Pan H, Griep A E

Abstract excerpt

Programmed cell death, or apoptosis, is a critical event in the development of multicellular organisms, and its perturbation is implicated in many diseases including cancer. The tumor suppressor protein p53 is known to mediate apoptosis induced by the DNA tumor virus oncoproteins, adenovirus E1A...

Topics

Animals
Animals, Newborn
Apoptosis
Eye Neoplasms
Genes, p53
Lens, Crystalline
Mice
Mice, Transgenic
Mutation
Oncogene Proteins, Viral
Papillomavirus E7 Proteins
Repressor Proteins
Tumor Suppressor Protein p53

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 7657167
DOI: 10.1101/gad.9.17.2157

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-7657167-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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