Patterning the fly eye: the role of apoptosis.

doi:10.1016/S0168-9525(02)00041-0

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Article

Patterning the fly eye: the role of apoptosis.

Trends in genetics : TIG - 1 Feb 2003

Brachmann Carrie Baker, Cagan Ross L

Abstract excerpt

Early development in many tissues is characterized by a rapid expansion in cell number. Excess cells are removed through activation of their intrinsic apoptotic machinery. This over-expansion followed by selective removal is important for the sculpting of these tissues, and how specific cells are selected to die is one of the central questions in development. The Drosophila eye is a unique example of such...

Topics

Animals
Apoptosis
Body Patterning
Caspases
Cell Death
Drosophila melanogaster
Embryo, Nonmammalian
Eye
Models, Biological
Mutation
Retina
Signal Transduction

Source

Open in PubMed

Identifiers

PMID: 12547518
DOI: 10.1016/S0168-9525(02)00041-0

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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