Article
Blocking apoptosis prevents blindness in Drosophila retinal degeneration mutants.
Nature - 5 Feb 1998
Davidson F F, Steller H
Abstract excerpt
Apoptosis is a gene-directed form of cell death that is essential for normal development and health. Yet abnormally high levels of apoptosis are linked to many degenerative diseases. Some important biochemical events in apoptosis have been identified, but the therapeutic utility of blocking cell...
Topics
- Animals
- Apoptosis
- Drosophila
- Electroretinography
- Humans
- Inhibitor of Apoptosis Proteins
- Mutation
- Photoreceptor Cells, Invertebrate
- Viral Proteins
- Vision, Ocular
