Biotransformation and pharmacokinetics of ethylmorphine after a single oral dose.

doi:10.1111/j.1365-2125.1995.tb05720.x

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Article

Biotransformation and pharmacokinetics of ethylmorphine after a single oral dose.

British journal of clinical pharmacology - 1 Jun 1995

Aasmundstad T A, Xu B Q, Johansson I, Ripel A, Bjørneboe A, Christophersen A S, Bodd E, Mørland J

Abstract excerpt

1. The pharmacokinetics of ethylmorphine after administration of a single dose of the cough mixture Cosylan were investigated in 10 healthy subjects. 2. The median urinary recovery of ethylmorphine and measured metabolites was 77% over 48 h. The median tmax of unchanged ethylmorphine was 45 min,...

Topics

Adult
Biotransformation
Cytochrome P-450 Enzyme System
Drug Administration Schedule
Ethylmorphine
Genotype
Glucuronates
Humans
Male
Morphine

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