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Article

Fatal and severe codeine intoxication in 3-year-old twins--interpretation of drug and metabolite concentrations.

International journal of legal medicine - 1 Sept 2009

Ferreirós Nerea, Dresen Sebastian, Hermanns-Clausen Maren, Auwaerter Volker, Thierauf Annette, Müller Christoph, Hentschel Roland, Trittler Rainer, Skopp Gisela, Weinmann Wolfgang

Abstract excerpt

This work presents two cases of codeine intoxication in 3-year-old monozygotic twin brothers while treated with a codeine slow-release formulation. One child had to be admitted to the hospital, whereas the other one died at home after aspiration of gastric content. The concentrations of codeine and major metabolites including morphine and corresponding glucuronide conjugates were measured by liquid...

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PMID: 19350261
DOI: 10.1007/s00414-009-0340-0

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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