Article
Complementation analysis of the murine scid cell line.
Radiation research - 1 Sept 1995
Zdzienicka M Z, Jongmans W, Oshimura M, Priestley A, Whitmore G F, Jeggo P A
Abstract excerpt
It has been shown that several X-ray-sensitive Chinese hamster cell mutants defective in repair of DNA double-strand breaks (DSBs) are also impaired in the process of V(D)J recombination. The hamster mutants with this phenotype represent three distinct complementation groups, represented by the x...
Topics
- Animals
- Cell Line
- Chromosomes, Human, Pair 8
- Cricetinae
- DNA Damage
- DNA Repair
- Genetic Complementation Test
- Humans
- Mice
- Mice, SCID
- Mutation