Article
Complementation analysis of the murine scid cell line.
Radiation research - 1 Sept 1995
Zdzienicka M Z, Jongmans W, Oshimura M, Priestley A, Whitmore G F, Jeggo P A
Abstract excerpt
It has been shown that several X-ray-sensitive Chinese hamster cell mutants defective in repair of DNA double-strand breaks (DSBs) are also impaired in the process of V(D)J recombination. The hamster mutants with this phenotype represent three distinct complementation groups, represented by the xrs series, XR-1 and V-3. The murine scid cell line also shows the same phenotype, and therefore we examined whether the...
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