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Article

Characterization of DNA polymerase beta mutants with amino acid substitutions located in the C-terminal portion of the enzyme.

Molecular & general genetics : MGG - 28 Jul 1995

Sweasy J B, Yoon M S

Abstract excerpt

We used quantitative complementation assays to characterize individual DNA polymerase beta (Pol beta) mutants for their ability to function in DNA replication and DNA repair. We also describe a screen for detecting mutator activity of DNA polymerase beta mutants. By using these bioassays, together with DNA polymerase activity gels, we characterized 15 new DNA polymerase beta mutants that display a wide spectrum...

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PMID: 7651344
DOI: 10.1007/BF02190803

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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