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Article

Isolation, characterization and transformation, by autonomous replication, of Mucor circinelloides OMPdecase-deficient mutants.

Molecular & general genetics : MGG - 28 Jul 1995

Benito E P, Campuzano V, Lŏpez-Matas M A, De Vicente J I, Eslava A P

Abstract excerpt

Pyrimidine auxotrophs of Mucor circinelloides were isolated after mutagenesis with nitrosoguanidine and selected for resistance to 5-fluoroorotate. These mutants were genetically and biochemically characterized and found to be deficient either in orotidine-5'-monophosphate decarboxylase (OMPdecase) activity or in orotate phosphoribosyl transferase (OPRTase) activity. Different circular DNA molecules containing...

Topics

Base Sequence
Blotting, Southern
DNA, Circular
Genes, Fungal
Mitosis
Molecular Sequence Data
Mucor
Mutation
Orotate Phosphoribosyltransferase
Orotidine-5'-Phosphate Decarboxylase

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Pyrimidines

Sequence Analysis

Transformation, Genetic

Source

Identifiers

PMID: 7651335
DOI: 10.1007/BF02190793

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-7651335-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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