Article
Regulation of pyrimidine biosynthesis in Pseudomonas cepacia.
Archives of microbiology - 1 Jan 1990
West T P, Chu C P
Abstract excerpt
Pyrimidine biosynthesis was investigated in Pseudomonas cepacia ATCC 17759. The presence of the de novo pyrimidine biosynthetic pathway enzyme activities was confirmed in this strain. Following transposon mutagenesis of the wild-type cells, a mutant strain deficient for orotidine 5'-monophosphate decarboxylase activity (pyrF) was isolated. Uracil, cytosine or uridine supported the growth of this mutant. Uracil...
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