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Article

Isolation, characterization and mapping of pyrimidine auxotrophs of Phycomyces blakesleeanus.

Current genetics - 1 Dec 1993

Campuzano V, del Valle P, de Vicente J I, Eslava A P, Alvarez M I

Abstract excerpt

A total of seven pyrimidine auxotrophs of Phycomyces were isolated from among 5-fluoroorotate acid (5-FOA)-resistant mutants. They were classified by complementation into two groups. A representative mutant strain belonging to one group was deficient in orotate phosphoribosyl transferase (OPRTase; EC 2.4.2.10) activity; the mutant strain belonging to the second group was deficient in orotidine-5'-monophosphate...

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PMID: 8299173
DOI: 10.1007/BF00351715

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