Article
Efficacy of a temperature-sensitive Sendai virus vaccine in hamsters.
Laboratory animal science - 1 Jun 1995
Tagaya M, Mori I, Miyadai T, Kimura Y, Ito H, Nakakuki K
Abstract excerpt
A temperature-sensitive HVJ-pB strain of parainfluenza type 1 (Sendai) virus was obtained from a persistently virus-infected cell culture. Intranasal inoculation of Syrian hamsters with the HVJ-pB temperature-sensitive mutant resulted in an abortive infection but induced a specific antibody response against Sendai virus without appreciable lesions in the respiratory tract. Prior exposure to the...
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