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Article

Isolation and characterization of temperature-sensitive mutants of Streptococcus suis: efficacy trial of the mutant vaccine in mice.

Veterinary microbiology - 1 Apr 1990

Kebede M, Chengappa M M, Stuart J G

Abstract excerpt

A model of experimental Streptococcus suis infection was developed in young mice. Minimum lethal dose (MLD) values were calculated for four virulent serotypes (1/2, 1, 2, 3) of S. suis using this model. Temperature-sensitive (ts) mutants of S. suis serotypes 1/2 and 1-8 were isolated and characterized on the basis of their growth kinetics and reversion rates. Ts mutants of S. suis 1/2, 1, 2, and 3 were tested as...

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Identifiers

PMID: 2353447
DOI: 10.1016/0378-1135(90)90112-9

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