Aerosol vaccination with a sendai virus temperature-sensitive mutant (HVJ-pB) derived from persistently infected cells.

doi:10.1093/infdis/162.2.402

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Article

Aerosol vaccination with a sendai virus temperature-sensitive mutant (HVJ-pB) derived from persistently infected cells.

The Journal of infectious diseases - 1 Aug 1990

Iwata H, Tagaya M, Matsumoto K, Miyadai T, Yokochi T, Kimura Y

Abstract excerpt

Experimental infections of mice with a Sendai virus temperature-sensitive (ts) mutant (HVJ-pB) were studied. Infection with the ts mutant induced the priming effect of interferon production and both humoral and cellular immune responses, although the ts mutant virus neither multiplied satisfactorily in the respiratory tracts of mice nor caused appreciable histopathologic lesions. Inoculation with the ts mutant...

Topics

Aerosols
Animals
Antibodies, Viral
Immunity, Cellular
Immunization, Passive
Interferons
Male
Mice
Mice, Inbred BALB C
Mice, Inbred CBA
Mice, Inbred DBA

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Mice, Nude

Mutation

Parainfluenza Virus 1, Human

Paramyxoviridae Infections

Respiratory System

Specific Pathogen-Free Organisms

Viral Vaccines

Source

Open in PubMed

Identifiers

PMID: 1695654
DOI: 10.1093/infdis/162.2.402

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1695654-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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